Tuesday, August 15, 2023

Smoking May Not Increase Systolic and Diastolic Blood Pressures



Background: We tried to understand whether there are some effects of smoking on systolic and diastolic blood pressures (BP).

Method: Consecutive daily smokers at least with six pack months and age and sex-matched non-smokers were taken into the study. Cases with regular alcohol consumption (one drink a day) for at least six months and patients with inflammatory, infectious, or devastating disorders or heart failure were excluded.

Results: The study included 247 smokers (173 males) and 167 non-smokers. Mean age of the smokers was 46.2 years, and 70.0% of them were males. Although the plasma triglycerides (163.1 versus 151.3 mg/dL, p<0.05), low density lipoproteins (LDL) (123.8 versus 117.5 mg/dL, p<0.05), erythrocyte sedimentation rate (ESR) (10.6 versus 9.3 mm/h, p<0.05), and C-reactive protein (CRP) (2.3 versus 2.0 mg/L, p<0.05) values were all higher in the smokers, the body weight, body mass index (BMI), and systolic and diastolic BP were not changed in them. On the other hand, high density lipoproteins (HDL) (40.9 versus 44.0 mg/dL, p<0.05) and fasting plasma glucose (FPG) (102.3 versus 111.6 mg/dL, p= 0.007) values and prevalence of diabetes mellitus (DM) (8.9% versus 14.3%, p<0.05) were all lower in the smokers.

Conclusion: Smoking causes a low-grade systemic inflammation on vascular endothelium terminating with an accelerated atherosclerosis-induced end-organ insufficiencies all over the body. Although the plasma triglycerides, LDL, ESR, and CRP were increased, and HDL, FPG, and DM were decreased in the smokers, the body weight, BMI, and systolic and diastolic BP were not changed in them, significantly.

Keywords: Smoking; Systolic Blood Pressure; Diastolic Blood Pressure; Triglycerides; Low Density Lipoproteins; High Density Lipoproteins; Fasting Plasma Glucose

Thursday, July 27, 2023

Biostatistical and Mathematical Analysis on Diversion Cover Plate During Covid-19 Pandemic



Submarine sailing under the water, because of the attack, misoperation, equipment failure, collision, fire and other factors, the risk of wreck always exists. How to escape and how to carry out effective rescue is a problem that needs to be solved for the navy of submarine owner country since submarine came into being. In order to improve the ability to float out of danger, some submarines are equipped with gas blowing equipment or hydrazine blowing equipment (two kinds of chemical liquid mixed to produce a large amount of high-pressure gas) for emergency ballast jetting, so that the submarine quickly drainage up to float. Some submarines are equipped with quick drift escape device and collective escape with buoyancy ball, buoyancy cylinder, etc. In this paper, the motion characteristics of a simplified diversion cover plate used for buoyancy ball are studied and a differential equation solution is given during COVID-19 pandemic.

Keywords: The submarine; Guide plate; Movement characteristics


As for the release device with the buoyancy ball, the resistance of the submarine in the course of moving is generally borne by the diversion cover plate above it. In case of danger, the diversion cover plate above the buoyancy ball needs to be unlocked by the mechanical locking device and can be opened smoothly and smoothly under the action of buoyancy. Therefore, it is of great significance to study the motion characteristics of fixed axis positive buoyancy diversion cover plate under water during COVID-19 pandemic [1].

Saturday, July 8, 2023

A Control Study of Apamargakshara in the Management of Benign Prostatic Hyperplasia


In Ayurvedic classics Mutraghata is the symptoms of low urinary output either by retention, absolute or relative anuria or oliguria Mutraghata and it is predominantly due to the Vata Dosha [1]. The Vata Dosha is responsible to expel the urine output timely as well as uniformly. If Vata gets vitiated, it causes various diseases in relation with Basti & produces Mutrarogas such as Prameha, Ashmari, Mutraghata, Mutrakruchcha. In Ayuraveda the Vatashtheela is a type of Mutraghata which may have some similarity with BPH based on symptoms such as Achala Unnata Granthi (singly movable & elevated), Vinmutranilasanga (retention of urine, faeces & flatus), Bastiadhmana and Vedanachaparabastou (excruciating pain in the bladder) [2]. BPH is the most common benign tumor in male patients, and its incidence is age related. Risk factor for the development of the BPH are not clearly understood. Some studies have suggested genetic predisposition, and some noted racial differences [3]. BPH is a senile disorder and chiefly affects individuals above the age of 50 years. The symptoms are those of BOO i.e. increased maturation frequency, dribbling, hesitancy, and the features of chronic urinary retention. In Ayuraveda Mutraghata was treated with Bhaishajya Chikitsa. Acharya Sushruta told general line of management of all type of Mutraghata with the use of Kashaya, Kalka, Avaleha, Kshar, Madhya, Aasava, Swedana Basti and Uttarbasti [4] so, it was decided to use Kshar in current study Apamargakshara is described in various diseases and used in indigenous medicine for treatment of diseases like Udararog, Mutrakruccha, Amadosa, Kaphavatavikar, Amavata, and some other complaints. According to Bhaishajyaratnavali, Apamargakshara is superior and best than other Kshara (alkali) as well as it can be used as a Lekhankarma, and it has diuretic property [5]. Apamargakshara is Katurasatmak in taste and Katu vipak, UshnaVirya, Vata, Kaphaghna in properties.

Tuesday, June 27, 2023

TCM Systematology: Ancient Wisdom Against Contemporary Global Crisis



In the era of globalization and pluralism, the world is constantly experiencing cultural conflicts, political divisions, and war killings. Mankind has not yet established a good policy to maintain world security. Because modern society lacks cultural wisdom matching globalization. Traditional Chinese medicine philosophy inherits the ancient cultural tradition, and its system balance theory and coordination thought have important inspiration for solving the crisis of modern society.

Keywords: TCM Philosophy; Human Crisis; System Thought; Ecological Synergy

Systematic Thinking Of TCM Helps to Construct a New Order of Globalization

The way out of the crisis lies in building high-level system thinking. Einstein said: “the answers to all difficult problems are at a higher level. It is difficult to solve problems at the same level by thinking at the same level. Only when your own cognitive level is improved can you successfully solve low-level problems, just like college students doing math problems for primary school students.” In view of the vulgar performances of primary school students on the international political stage, we need the University thinking of traditional Chinese medicine philosophy [1].

TCM classics such as the《nner Canon of Huangdi》《Treatise on typhoid feve》and others contain the idea of ecological balance and harmonious social development: the human body is regarded as an active system restricted by various natural factors, and local diseases are considered in the whole system clinically, so that the body can heal itself by regulating the meridian system. For example, traditional Chinese medicine believes that ear acupoints correspond to whole body organs through meridians and collaterals and stimulating ear acupoints can adjust and improve the state of corresponding systems and bodies. Similarly, tongue color and shape changes can also be used as a diagnostic basis. This is the dialectical method of TCM bio holography in clinic and diagnosis. Use the energy of the human body to solve health problems [2,3].

We can use this systematic thinking model for reference to analyze isolated international events in the globalization system. For example, the Ukraine Russia war is a political contest between the European and American camps and the two camps composed of Russia, China and other countries. Systemic advantage is the key to victory. TCM is good at predicting the future development of the situation through hidden factors. This is what modern human society lacks.

Tuesday, June 13, 2023

Bioremediation of Cypermethrin by Laccase Producing Bacteria



Increased urbanization and industries has led to the production, accumulation and incorporation of contaminant into the ecosystems, distorting and impacting, plant, human and animal health. Several physical, chemical, and biological strategies have been adopted to eliminate these contaminants from soil and water bodies. Biotechnological processes involving microorganisms and enzymes have been widely used for this purpose; specifically, laccases, which is a versatile enzyme which catalyse oxidation reaction coupled to four- electron reduction of molecular oxygen to water. Laccases 1, 4-benzenediol oxygen oxidoreductase, are also called as “Blue Enzyme” as they are multinuclear copper containing enzymes. Laccase belongs to the superfamily of multicopper oxidases (MCOs)—a group of enzymes comprising many proteins with different substrate specificities and diverse biological functions. are broad spectrum biocatalysts, have been used to degrade several compounds, such as those that can be found in the effluents from industries and hospitals. Cypermethrin is an organophosphorus pesticide, belonging to a group of synthetic pyrethroid insecticides which are analogous of naturally occurring pyrethrins of botanical origin. It is widely used in agriculture, forestry, Horticulture, public health, and households for the protection of textiles and to check pest infestation. The present investigation is therefore carried out to study the potential of bacterial laccase in the biodegradation of Cypermethrin.

Keywords: Laccase; Bacteria; Bioremediation; Cypermethrin


Laccase belongs to the enzyme family of multi- copper oxidases (MCOs), are classified as benzenediol oxygen reductases and are also known as Uracil oxidases and p-diphenol oxidases. The term ‘Laccase’ stems from its original identification in the exudates of the Japanese lacquer tree Rhusver nicifera described by Yoshida (1883). Just over a century later, it was characterized as being a metal-containing oxidase depicted by Bertrand (1985). Laccase can catalyse the oxidation of various organic and inorganic compounds including diphenols, polyphenols, diamines, substituted phenols, and aromatic amines with reduction of molecular oxygen to water. Laccase also oxidizes other substrates such as aromatic amines, syringaldazine, 2,2-azinobis(3-ethylbenzothiazoline6-sulphonate) and 1hydroxybenzotriazole, 2,2,6,6-tetrametylpiperidineoxy (TEMPO), violuric acid to form free radicals (Zille et al., 2003).

Monday, April 10, 2023

Multi-Modal Paths in Rural Appalachia to Improve Local Transportation Opportunities: a Case Study



Transportation is a public health problem in the rural Appalachian region of the United States. Furthermore, access to outdoor physical activity facilities and transportation to schools is limited and difficult to establish. This case study aims to highlight assets and problems sur-rounding transportation in rural Appalachia and how advocacy for multi-modal lanes can be beneficial to address the important need to improve transportation. Improving multi-modal forms of transportation can provide many benefits within a community and can positively impact different populations. If we improve transportation, all health outcomes change. Additionally, new growth by way of multi-modal transportation creates demand for new housing, business, and community. Harmony Lanes is a local non-profit in rural Northwestern North Carolina formed to fulfill a mission: “Create safe, inclusive multi-modal infrastructure.” Their purpose is to identify what worked in the past so that we (and others) can aim to replicate those steps in order to be successful. This case study examines the timeline and actions taken to organize people, the community, and leaders to make a small change in transportation to improve rural mobility in the Appalachians.

Read more Lupine Publishers Google Scholar Articles :   https://scholar.google.com/citations?view_op=view_citation&hl=en&user=0sWAIssAAAAJ&citation_for_view=0sWAIssAAAAJ:p2g8aNsByqUC

Wednesday, March 29, 2023

The Anti-Asian American Pacific Islander Bias Survey: Anti- Asian Bias Spectrum from Microaggressions to Violence



Background: Anti-Asian bias is not a new phenomenon. The murders of eight victims at spas in Georgia with six of the victims being Asian women has caused a new generation to speak up about the discrimination that is directed toward those who identify as Asian American Pacific Islanders (AAPI).

Objectives: The brief Anti-Asian American Pacific Islander Bias Survey (AAAPIBS) was developed to view how discrimination shows up from microaggressions to violence on the spectrum of Anti-Asian bias.

Methodology: A convenience sample of occupational therapy practitioners and Asian American women in academia in the U.S. were given the survey.

Results: Anti-Asian discrimination occurs on a spectrum which has two major themes: Perpetual Foreigner and Model Minority. One new item emerged which was cultural appropriation from AAPI practices which are sources of cultural strengths and support, e.g. Mindfulness.

Implications: Anti-AAPI bias hinders the complete participation of AAPI Peoples in our society.

Keywords: Cultural appropriation; Envied Outgroup; Microaggressions; Model Minority; Perpetual Foreigner

Smoking May Not Increase Systolic and Diastolic Blood Pressures

  Abstract Background: We tried to understand whether there are some effects of smoking on systolic and diastolic blood pressure...