Saturday, July 8, 2023

A Control Study of Apamargakshara in the Management of Benign Prostatic Hyperplasia

Introduction

In Ayurvedic classics Mutraghata is the symptoms of low urinary output either by retention, absolute or relative anuria or oliguria Mutraghata and it is predominantly due to the Vata Dosha [1]. The Vata Dosha is responsible to expel the urine output timely as well as uniformly. If Vata gets vitiated, it causes various diseases in relation with Basti & produces Mutrarogas such as Prameha, Ashmari, Mutraghata, Mutrakruchcha. In Ayuraveda the Vatashtheela is a type of Mutraghata which may have some similarity with BPH based on symptoms such as Achala Unnata Granthi (singly movable & elevated), Vinmutranilasanga (retention of urine, faeces & flatus), Bastiadhmana and Vedanachaparabastou (excruciating pain in the bladder) [2]. BPH is the most common benign tumor in male patients, and its incidence is age related. Risk factor for the development of the BPH are not clearly understood. Some studies have suggested genetic predisposition, and some noted racial differences [3]. BPH is a senile disorder and chiefly affects individuals above the age of 50 years. The symptoms are those of BOO i.e. increased maturation frequency, dribbling, hesitancy, and the features of chronic urinary retention. In Ayuraveda Mutraghata was treated with Bhaishajya Chikitsa. Acharya Sushruta told general line of management of all type of Mutraghata with the use of Kashaya, Kalka, Avaleha, Kshar, Madhya, Aasava, Swedana Basti and Uttarbasti [4] so, it was decided to use Kshar in current study Apamargakshara is described in various diseases and used in indigenous medicine for treatment of diseases like Udararog, Mutrakruccha, Amadosa, Kaphavatavikar, Amavata, and some other complaints. According to Bhaishajyaratnavali, Apamargakshara is superior and best than other Kshara (alkali) as well as it can be used as a Lekhankarma, and it has diuretic property [5]. Apamargakshara is Katurasatmak in taste and Katu vipak, UshnaVirya, Vata, Kaphaghna in properties.


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